Soyasapogenol A

Soyasapogenol A

• CAS Number: 508-01-0
• UNSPSC Description: Soyasapogenol A, a triterpene compound, isolated from soybean. Soyasapogenol A directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently results in the prevention of liver damage in the Concanavalin A-induced hepatitis model[1][2].
• Target Antigen: Apoptosis
• Type: Natural Products
• Related Pathways: Apoptosis
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/soyasapogenol-a.html
• Purity: 99.06
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: C[C@]12[C@]3(C([C@@]4([H])[C@](C)([C@@H]([C@H](O)C(C)(C)C4)O)CC3)=CC[C@]1([H])[C@@]5([C@@]([C@](C)([C@@H](O)CC5)CO)([H])CC2)C)C
• Molecular Weight: 474.72
• References & Citations: [1]Chiang TC, et al. Isolation and structural elucidation of some sapogenols from Abrus cantoniensis. Planta Med. 1982 Sep;46(1):52-5.|[2]Kuzuhara H, et al. Protective effects of soyasapogenol A on liver injury mediated by immune response in a concanavalin A-induced hepatitis model. Eur J Pharmacol. 2000 Mar 10;391(1-2):175-81.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported