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Nomegestrol acetate

CAT:
804-HY-105634A-03
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Nomegestrol acetate - image 1

Nomegestrol acetate

  • CAS Number: 58652-20-3
  • UNSPSC Description: Nomegestrol acetate is an orally active, highly selective progestogen and a progesterone receptor complete agonist. Nomegestrol acetate inhibits ovulation. Nomegestrol acetate is also effective in inhibiting the proliferation of human endometrial cancer RL95-2 cells in vitro and in vivo. Nomegestrol acetate can be used in cancer (especially endometrial cancer) and contraceptive studies[1][2][3].
  • Target Antigen: Progesterone Receptor
  • Type: Reference compound
  • Related Pathways: Vitamin D Related/Nuclear Receptor
  • Applications: Neuroscience-Neuromodulation
  • Field of Research: Cancer; Endocrinology
  • Assay Protocol: https://www.medchemexpress.com/nomegestrol-acetate.html
  • Purity: 99.94
  • Solubility: DMSO : 62.5 mg/mL (ultrasonic)
  • Smiles: CC([C@@]1(OC(C)=O)CC[C@@]2([H])[C@]3([H])C=C(C)C4=CC(CC[C@]4([H])[C@@]3([H])CC[C@]12C)=O)=O
  • Molecular Weight: 370.48
  • References & Citations: [1]Mueck AO, et al. Nomegestrol acetate, a novel progestogen for oral contraception. Steroids. 2011 May;76(6):531-9.|[2]Ma AY, et al. Nomegestrol Acetate Suppresses Human Endometrial Cancer RL95-2 Cells Proliferation In Vitro and In Vivo Possibly Related to Upregulating Expression of SUFU and Wnt7a. Int J Mol Sci. 2017 Jun 22;18(7):1337.|[3]van Diepen HA, et al. Nomegestrol acetate: steroid receptor transactivation profile in Chinese hamster ovary cells and ovulation inhibition in rat and monkey. Contraception. 2011 Aug;84(2):199-204.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
  • Clinical Information: Launched