DT-6
CAT:
804-HY-156512-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DT-6
- CAS Number: 2414315-95-8
- UNSPSC Description: DT-6 is an effective TGF-β1 inhibitor. DT-6 inhibits M2 macrophage induced epithelial to mesenchymal transition and invasive migration of cancer cells. DT-6 can be used for cancer diseases research[1].
- Target Antigen: TGF-beta/Smad
- Type: Reference compound
- Related Pathways: Stem Cell/Wnt;TGF-beta/Smad
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/dt-6.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C1C2=C(OCC(NCCCCCC(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCSC)C(N[C@@H](CCSC)C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C=CC=C2C(N1C5C(NC(CC5)=O)=O)=O
- Molecular Weight: 2008.23
- References & Citations: [1]Feng Y, et al. Degradation of intracellular TGF-β1 by PROTACs efficiently reverses M2 macrophage induced malignant pathological events. Chem Commun (Camb). 2020 Mar 5;56(19):2881-2884.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported