Metronidazole (hydrochloride)

Metronidazole (hydrochloride)

• CAS Number: 69198-10-3
• UNSPSC Description: Metronidazole hydrochloride (SC 326421) is an orally active nitroimidazole antibiotic, can be used to research anaerobic infections. Metronidazole hydrochloride can cross blood brain barrier and results inflammation and skeletal muscle contraction under long-term application[1][2][3][4].
• Target Antigen: Antibiotic; Apoptosis; Bacterial; Parasite
• Type: Reference compound
• Related Pathways: Anti-infection;Apoptosis
• Applications: COVID-19-immunoregulation
• Field of Research: Infection; Inflammation/Immunology; Cancer
• Assay Protocol: https://www.medchemexpress.com/metronidazole-hydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: OCCN1C([N+]([O-])=O)=CN=C1C.[H]Cl
• Molecular Weight: 207.61
• References & Citations: [1]Scully BE. Metronidazole. Med Clin North Am. 1988 May;72(3):613-21.|[2]Dhurga DB, et al. Granular Formation during Apoptosis in Blastocystis sp. Exposed to Metronidazole (MTZ). PLoS One. 2016 Jul 29;11(7):e0155390.|[3]Chaturvedi S, et al. Mechanistic exploration of quercetin against metronidazole induced neurotoxicity in rats: Possible role of nitric oxide isoforms and inflammatory cytokines. Neurotoxicology. 2020 Jul;79:1-10.|[4]Manickam R, et al. Metronidazole Causes Skeletal Muscle Atrophy and Modulates Muscle Chronometabolism. Int J Mol Sci. 2018 Aug 16;19(8):2418.
• Shipping Conditions: Room temperature
• Clinical Information: Launched