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Oseltamivir-d5 (phosphate)

CAT:
804-HY-17016S
Size:
1 mg
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Oseltamivir-d5 (phosphate) - image 1

Oseltamivir-d5 (phosphate)

  • UNSPSC Description: Oseltamivir-d5 (phosphate) is the deuterium labeled Oseltamivir phosphate. Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B[1][2].
  • Target Antigen: Influenza Virus; Isotope-Labeled Compounds
  • Type: Isotope-Labeled Compounds
  • Related Pathways: Anti-infection;Others
  • Field of Research: Infection
  • Solubility: 10 mM in DMSO
  • Smiles: N[C@H]1CC(C(OC(C([2H])([2H])[2H])([2H])[2H])=O)=C[C@H]([C@@H]1NC(C)=O)OC(CC)CC.O=P(O)(O)O
  • Molecular Weight: 415.43
  • References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]de Oliveira JT, et al. Anti-influenza neuraminidase inhibitor Oseltamivir phosphate induces canine mammary cancer cell aggressiveness. PLoS One. 2015 Apr 7;10(4):e0121590.|[3]Huang H, et al. Transplacental transfer of Oseltamivir phosphate and its metabolite Oseltamivir carboxylate using the ex vivo human placenta perfusion model in Chinese Hans population. J Matern Fetal Neonatal Med. 2016 Aug 8:1-5.|[4]Li P, et al. A Simple and Robust Approach for Evaluation of Antivirals Using a Recombinant Influenza Virus Expressing Gaussia Luciferase. Viruses. 2018 Jun 13;10(6). pii: E325.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported