PDH E1-IN-1
CAT:
804-HY-161048
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PDH E1-IN-1
- UNSPSC Description: PDH E1-IN-1 (compound 24) is a selective TPP-competitive PDH E1 with an IC50 value of 0.99 μM[1].
- Target Antigen: Others; PDHK
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease;Others
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/pdh-e1-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: CC1=NC=C(C(N)=N1)CC2=CSC(CCNC3(C4=CC=C(C=C4)OC)COC3)=C2C
- Molecular Weight: 424.56
- References & Citations: [1]Alex H Y Chan, et al. Thiamine analogues featuring amino-oxetanes as potent and selective inhibitors of pyruvate dehydrogenase. Bioorg Med Chem Lett. 2023.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported