SRE-II
CAT:
804-HY-155070
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SRE-II
- UNSPSC Description: SRE-II, an amide derivative, is an activatable photosensitizer for photodynamic cancer research with decreased fluorescence and photosensitizing capabilities. SRE-II can be further converted into the active photosensitizer SDU Red via carboxylesterase-catalyzed amide bond cleavage. SRE-II induces DNA damage and cell apoptosis in the presence of light. SRE-II can act as a promising theranostic agent for triple-negative breast cancer[1].
- Target Antigen: Apoptosis; DNA/RNA Synthesis
- Type: Reference compound
- Related Pathways: Apoptosis;Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/sre-ii.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C=C1)C2=CC=CC3=C(NC(CCl)=O)C(I)=CC1=C32
- Molecular Weight: 397.59
- References & Citations: [1]Qiaoyun Jiang, et al. Lysosome-targeting phenalenones as efficient type I/II photosensitizers for anticancer photodynamic therapy. Eur J Med Chem. 2023 Jul 5;255:115418.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported