5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite

CAT:

804-HY-154721

Size:

Inquire

Price:

Ask

For price, please contact [email protected]

CAS Number: 178925-48-9
UNSPSC Description: 5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/5-o-dmtr-5-iodo-2-du-3-ced-phosphoramidite.html
Solubility: 10 mM in DMSO
Smiles: O=C(N1[C@H](O2)C[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H]2COC(C3=CC=C(C=C3)OC)(C4=CC=CC=C4)C5=CC=C(C=C5)OC)NC(C(I)=C1)=O
Molecular Weight: 856.68
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-154721	5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite
HY-154238	5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite
HY-134337	5'-O-DMTr-3'-O-methyl uridine-3'-CED-phosphoramidite
HY-W545104-04	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
HY-W545104-03	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
HY-154264	5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite
HY-W545104-01	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
HY-W545104-02	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
HY-154351	N2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite
HY-154222	5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

Cat	Name
TNU1514-1g	5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite
TNU1514-50mg	5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite
MBS5827103	5'-O-DMTr-3'-deoxyuridine 2'-CED phosphoramidite
TNU1514-10mg	5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite
TNU1514-1mg	5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite
TNU1514-5mg	5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite
TNU0676-1g	5’-O-DMTr-2’-deoxy-5-iodouridine-3’-CED Phosphoramidite
TNU0676-50mg	5’-O-DMTr-2’-deoxy-5-iodouridine-3’-CED Phosphoramidite
TNU0676-10mg	5’-O-DMTr-2’-deoxy-5-iodouridine-3’-CED Phosphoramidite
TNU1619-5mg	5’-O-DMTr-2’-O-methyl-5-methyluridine 3’-CED phosphoramidite