N4-(3,3,3-Trifluoropropanoyl)cytidine
CAT:
804-HY-154151
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
N4-(3,3,3-Trifluoropropanoyl)cytidine
- UNSPSC Description: N4-(3,3,3-Trifluoropropanoyl)cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
- Target Antigen: Nucleoside Antimetabolite/Analog
- Type: Oligonucleotides
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/n4-3-3-3-trifluoropropanoyl-cytidine.html
- Solubility: 10 mM in DMSO
- Smiles: OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(NC(CC(F)(F)F)=O)C=C2)=O)O1
- Molecular Weight: 353.25
- References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported