5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine

5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine

• CAS Number: 89128-99-4
• UNSPSC Description: 5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/5-methyl-2-2-2-trifluoroacetyl-amino-methyl-2-thiouridine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@@H](O)[C@H](N2C=C(CN(C)C(C(F)(F)F)=O)C(NC2=S)=O)O[C@@H]1CO
• Molecular Weight: 399.34
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported