2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine
CAT:
804-HY-152689
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine
- CAS Number: 2072145-77-6
- UNSPSC Description: 2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
- Target Antigen: Nucleoside Antimetabolite/Analog
- Type: Oligonucleotides
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/2-deoxy-2-fluoro-n3-4-nitrobenzyl-beta-d-arabinouridine.html
- Solubility: 10 mM in DMSO
- Smiles: OC[C@@H]1[C@@H](O)[C@H](F)[C@H](N(C=CC2=O)C(N2CC3=CC=C([N+]([O-])=O)C=C3)=O)O1
- Molecular Weight: 381.31
- References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported