3’-Beta-C-ethynyl-N6-(m-methoxybenzyl)adenosine

3’-Beta-C-ethynyl-N6-(m-methoxybenzyl)adenosine

• UNSPSC Description: 3’-Beta-C-ethynyl-N6-(m-methoxybenzyl)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. 3’-Beta-C-ethynyl-N6-(m-methoxybenzyl)adenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/3-beta-c-ethynyl-n6-m-methoxybenzyl-adenosine.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC(CNC2=NC=NC3=C2N=CN3[C@H]4[C@H](O)[C@](O)(C#C)[C@@H](CO)O4)=CC=C1
• Molecular Weight: 411.41
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.|[2]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported