1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine

1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine

• CAS Number: 2389988-21-8
• UNSPSC Description: 1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/1-amino-7-8-dihydro-8-oxo-9-β-d-xylofuranosyl-guanine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@@H](O)[C@H](N(C(N2)=O)C3=C2C(N(N)C(N)=N3)=O)O[C@@H]1CO
• Molecular Weight: 314.25
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported