HSP90-IN-18

HSP90-IN-18

• CAS Number: 2927442-45-1
• UNSPSC Description: HSP90-IN-18 is an effective heat shock protein 90 (Hsp90) inhibitor. HSP90-IN-18 has effective Hsp90 inhibitory activity with an IC50 value of 0.39 μM. HSP90-IN-18 can be used for the research of viral infection, neurodegenerative disease, and inflammation[1].
• Target Antigen: Apoptosis; HSP
• Type: Reference compound
• Related Pathways: Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Cancer; Infection; Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/hsp90-in-18.html
• Solubility: 10 mM in DMSO
• Smiles: C/C(C)=C\CC[C@]1(CC=C(C2=C([C@@H]1/C=C/OC(/C=C(C)/C)=O)C=C(O2)C)CF)C
• Molecular Weight: 400.53
• References & Citations: [1]Meng Li, et al. Design, synthesis and biological evaluation of a new class of Hsp90 inhibitors vibsanin C derivatives. Eur J Med Chem. 2022 Dec 15;244:114844.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported