SphK1-IN-3
CAT:
804-HY-148262
Size:
Inquire
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SphK1-IN-3
- UNSPSC Description: SphK1-IN-3 is an effective sphingosine kinase-1 (SphK1) inhibitor. SphK1-IN-3 inhibits SphK1 kinase activity with an IC50 value of 2.48 μM. SphK1-IN-3 can be used for the research of many diseases such as cancer, rheumatoid arthritis, diabetes, asthma, and pulmonary fibrosis[1].
- Target Antigen: SphK
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/sphk1-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: O=[N+](C1=CC=C2NC(C3=C(N4CCOCC4)N(C5=CC=CC=C5)N=C3C)=NC2=C1)[O-]
- Molecular Weight: 404.42
- References & Citations: [1]Shadia A. Galal, et al. Design and synthesis of new pyrazolylbenzimidazoles as sphingosine kinase-1 inhibitors. Med Chem Res 30, 1614–1634 (2021).
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported