hCAIX/XII-IN-3
CAT:
804-HY-146258
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
hCAIX/XII-IN-3
- CAS Number: 2414629-94-8
- UNSPSC Description: hCAIX/XII-IN-3 (compound 6q) is a potent and selective hCAIX and hCAXIIinhibitor with Ki values of >10000, >10000, 66.2, 4.4 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].
- Target Antigen: Carbonic Anhydrase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hcaix-xii-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: O=C1C=C(C)C2=C(O1)C=C(OCC3=NOC(C4=CC=C(C(F)(F)F)C=C4)=N3)C=C2
- Molecular Weight: 402.32
- References & Citations: [1]Thacker PS, et al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported