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3'OMe-m7GpppAmpG

CAT:
804-HY-145973
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
3'OMe-m7GpppAmpG - image 1

3'OMe-m7GpppAmpG

  • CAS Number: 2089461-55-0
  • UNSPSC Description: 3'OMe-m7GpppAmpG is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG shows a significant translational efficiency. 3'OMe-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization[1].
  • Target Antigen: DNA/RNA Synthesis
  • Type: Oligonucleotides
  • Related Pathways: Cell Cycle/DNA Damage
  • Applications: Cancer-programmed cell death
  • Field of Research: Others
  • Assay Protocol: https://www.medchemexpress.com/3-ome-m7gpppampg.html
  • Solubility: 10 mM in DMSO
  • Smiles: O[C@@H]1[C@H](OC)[C@@H](COP(OP(OP(OC[C@@H]2[C@@H](OP([O-])(OC[C@@H]3[C@@H](O)[C@@H](O)[C@H](N4C(N=C(N)NC5=O)=C5N=C4)O3)=O)[C@@H](OC)[C@H](N6C(N=CN=C7N)=C7N=C6)O2)(O)=O)(O)=O)(O)=O)O[C@H]1N8C(N=C(N)NC9=O)=C9[N+](C)=C8
  • Molecular Weight: 1159.69
  • References & Citations: [1]Senthilvelan A, et al. Trinucleotide Cap Analogue Bearing a Locked Nucleic Acid Moiety: Synthesis, mRNA Modification, and Translation for Therapeutic Applications. Org Lett. 2021 Jun 4;23(11):4133-4136.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported