JAK1-IN-9
CAT:
804-HY-144440
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JAK1-IN-9
- CAS Number: 2875041-96-4
- UNSPSC Description: JAK1-IN-9 (compound 23a) is a potent and selective JAK1 inhibitor with an IC50 of 72 nM. JAK1-IN-9 shows selective against other JAKs by 12 times or more[1].
- Target Antigen: JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/jak1-in-9.html
- Solubility: 10 mM in DMSO
- Smiles: CC1=C(N=NN1CC2=CC=C(C=C2)I)C3=C4C=CNC4=NC=N3
- Molecular Weight: 416.22
- References & Citations: [1]WooChan Kim, et al. Synthesis and structure-activity relationship studies of 1,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 1 (JAK1) inhibitors. Bioorg Med Chem Lett. 2022 Jan 1;55:128451.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported