hAChE/Aβ1-42-IN-1
CAT:
804-HY-144389
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
hAChE/Aβ1-42-IN-1
- CAS Number: 2761149-17-9
- UNSPSC Description: hAChE/Aβ1-42-IN-1 (Compound 16) is a potent inhibitor of hAChE and Aβ1-42 aggregation. hAChE/Aβ1-42-IN-1 shows acceptable relative safety upon hepG2 cell line and excellent BBB penetration with wide safety margin. hAChE/Aβ1-42-IN-1 has the potential for the research of Alzheimer disease (AD)[1].
- Target Antigen: Amyloid-β; Cholinesterase (ChE)
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/hache-aβ1-42-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=NNC2=NC=CC=C21)CCN3CCN(CC3)CC4=CC=CC=C4
- Molecular Weight: 364.44
- References & Citations: [1]Waly OM, et al. Synthesis, biological evaluation, and molecular modeling simulations of new heterocyclic hybrids as multi-targeted anti-Alzheimer's agents. Eur J Med Chem. 2022;231:114152.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported