JAK3/BTK-IN-2
CAT:
804-HY-143717
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JAK3/BTK-IN-2
- CAS Number: 2674036-93-0
- UNSPSC Description: JAK3/BTK-IN-2 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets for autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway exhibits synergistic effects. JAK3/BTK-IN-2 has the potential for the research of JAK3 kinase and/or BTK-related diseases (extracted from patent WO2021147952A1, compound 004)[1]
- Target Antigen: Btk; JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/jak3-btk-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: C=CC(N1C[C@H](NC2=C3C(NC=C3C4CC4)=NC(NC5=CN(C6CCOCC6)N=C5)=N2)CCC1)=O
- Molecular Weight: 476.57
- References & Citations: [1]Guobao Zhang, et al. Pyrimidopyrroles. Patent WO2021147952A1.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported