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Pomalidomide-6-O-CH3

CAT:
804-HY-139542
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Pomalidomide-6-O-CH3 - image 1

Pomalidomide-6-O-CH3

  • CAS Number: 1547163-08-5
  • UNSPSC Description: Pomalidomide-6-O-CH3 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-O-CH3 can be connected to the ligand for protein by a linker to form PROTAC[1].
  • Target Antigen: Ligands for E3 Ligase
  • Type: Reference compound
  • Related Pathways: PROTAC
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/pomalidomide-6-o-ch3.html
  • Solubility: 10 mM in DMSO
  • Smiles: O=C1C2=C(C(N1C3C(NC(CC3)=O)=O)=O)C(N)=CC(OC)=C2
  • Molecular Weight: 303.27
  • References & Citations: [1]Andrew J. Phillips, et al. Bromodomain targeting degronimers for target protein degradation. WO2017197056A1.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported