Azido-PEG10-propargyl

Azido-PEG10-propargyl

• UNSPSC Description: Azido-PEG10-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG10-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/azido-peg10-propargyl.html
• Solubility: 10 mM in DMSO
• Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
• Molecular Weight: 521.60
• References & Citations: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-998.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported