5-Propargylamino-3'-azidomethyl-dUTP

5-Propargylamino-3'-azidomethyl-dUTP

• CAS Number: 666847-57-0
• UNSPSC Description: 5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 5. 5-Propargylamino-3'-azidomethyl-dUTP can be used in DNA synthesis and DNA sequencing[1]. 5-Propargylamino-3'-azidomethyl-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
• Target Antigen: DNA/RNA Synthesis
• Type: Biochemical Assay Reagents
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/5-propargylamino-3-azidomethyl-dutp.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N([C@H]2C[C@H](OCN=[N+]=[N-])[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)C=C(C(N1)=O)C#CCN
• Molecular Weight: 576.24
• References & Citations: [1]Milton J, et, al. Modified nucleotides for polynucleotide sequencing. WO2004018497A2.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported