PI3K/HDAC-IN-1

PI3K/HDAC-IN-1

• CAS Number: 2361418-52-0
• UNSPSC Description: PI3K/HDAC-IN-1 is a potent dual inhibitor of PI3K/HDAC, potently inhibits PI3Kδ and HDAC1 with IC50s of 8.1 nM and 1.4 nM, respectively[1].
• Target Antigen: HDAC; PI3K
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pi3k-hdac-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=C2C(C(OCCCCCCC(NO)=O)=CC(C3=CC(F)=C(OC)N=C3)=C2)=NC=N1
• Molecular Weight: 428.46
• References & Citations: [1]Zhang K, et al. Design, Synthesis, and Biological Evaluation of 4-Methyl Quinazoline Derivatives as Anticancer Agents Simultaneously Targeting Phosphoinositide 3-Kinases and Histone Deacetylases. J Med Chem. 2019 May 29.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported