Nek2-IN-5
CAT:
804-HY-120330
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nek2-IN-5
- CAS Number: 1507367-00-1
- UNSPSC Description: Nek2-IN-5 (compound 6) is a potent and irreversible Nek2 ((Never in mitosis gene a)-related kinase 2) inhibitior[1]. Nek2-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Target Antigen: NEKs
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/nek2-in-5.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(CC1=CC=CC(NC2=NC(C#C)=C3N=CNC3=N2)=C1)N
- Molecular Weight: 292.30
- References & Citations: [1]Lebraud H, et al. Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocycles. Org Biomol Chem. 2014 Jan 7;12(1):141-8.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported