L-(+)-threo-Chloramphenicol

L-(+)-threo-Chloramphenicol

• CAS Number: 134-90-7
• UNSPSC Description: L-(+)-threo-Chloramphenicol ((+)-Chloramphenicol) is the S,S-stereoisomer of Chloramphenicol (HY-B0239). L-(+)-Threo-chloramphenicol inhibits protein synthesis in reticulocytes. L-(+)-threo-Chloramphenicol also inhibits the oxidative activity of isolated mitochondria[1][2].
• Target Antigen: Antibiotic
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/l-plus-threo-chloramphenicol.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C(Cl)Cl)N[C@H]([C@H](C1=CC=C(C=C1)[N+]([O-])=O)O)CO
• Molecular Weight: 323.13
• References & Citations: [1]3rd WG, et, al. The effect of chloramphenicol in intact erythroid cells. J Mol Biol. 1966 Nov 28;21(3):537-53. |[2]Gordon PA, et, al. Effects of chloramphenicol isomers and erythromycin on enzyme and lipid synthesis induced by oxygen in wild-type and petite yeast. J Bacteriol. 1972 May;110(2):504-10.
• Shipping Conditions: Room temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported