AKT-IN-2
CAT:
804-HY-112148
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AKT-IN-2
- CAS Number: 1295514-91-8
- UNSPSC Description: AKT-IN-2 is a potent, selective and orally bioavailable AKT inhibitor with an IC50 of 5 nM for AKT1[1].
- Target Antigen: Akt
- Type: Reference compound
- Related Pathways: PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/AKT-IN-2.html
- Solubility: 10 mM in DMSO
- Smiles: O=C1C[C@@H](C)C2=C(N3CCC(C4=NC(CCC(F)(F)F)=CN4CCN5CCCC5)CC3)N=CN=C2N1
- Molecular Weight: 505.58
- References & Citations: [1]Parthasarathy S, et al. Discovery of chiral dihydropyridopyrimidinones as potent, selective and orally bioavailable inhibitors of AKT. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1887-1891.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported