Login

PARP-2/1-IN-2

CAT:
804-HY-105253
Size:
Inquire
Price:
Ask
For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
PARP-2/1-IN-2 - image 1

PARP-2/1-IN-2

  • CAS Number: 912444-01-0
  • UNSPSC Description: PARP-2/1-IN-2 (Compound 4a), the enantiomer of Veliparib (HY-10129), is a potent PARP inhibitor with Kis of 2 and 5 nM against PARP-2 and PARP-1, respectively. PARP-2/1-IN-2 has an EC50 of 3 nM in a cell based assay of PARP activity[1].
  • Target Antigen: PARP
  • Type: Reference compound
  • Related Pathways: Cell Cycle/DNA Damage;Epigenetics
  • Applications: Neuroscience-Neuromodulation
  • Field of Research: Neurological Disease
  • Assay Protocol: https://www.medchemexpress.com/parp-2-1-in-2.html
  • Solubility: 10 mM in DMSO
  • Smiles: NC(C1=C2C(N=C([C@]3(C)CCCN3)N2)=CC=C1)=O
  • Molecular Weight: 244.29
  • References & Citations: [1]Ta LE, et al. A novel and selective poly (ADP-ribose) polymerase inhibitor ameliorates chemotherapy-induced painful neuropathy. PLoS One. 2013;8(1):e54161.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported