(R)-(-)-O-Desmethyl Venlafaxine-d6

(R)-(-)-O-Desmethyl Venlafaxine-d6

• CAS Number: 1062609-96-4
• UNSPSC Description: (R)-(-)-O-Desmethyl Venlafaxine-d6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].
• Target Antigen: Drug Metabolite; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Solubility: 10 mM in DMSO
• Smiles: OC1([C@H](C2=CC=C(O)C=C2)CN(C([2H])([2H])[2H])C([2H])([2H])[2H])CCCCC1
• Molecular Weight: 269.41
• References & Citations: [1]Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28.|[2]F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported