Pomalidomide-PEG2-OMs

Pomalidomide-PEG2-OMs

• CAS Number: 2140807-37-8
• UNSPSC Description: Pomalidomide-PEG2-Oms (CRBN ligand Pomalidomide (HY-10984)) is an E3 Ligase Ligand-Linker Conjugate for EGFR PROTAC DDC-01-163 (HY-139997)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pomalidomide-peg2-oms.html
• Smiles: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOS(=O)(C)=O)=CC=C3)=O)=O
• Molecular Weight: 483.49
• References & Citations: [1]Jaebong Jang, et al. Mutant-Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug-Resistant Mutations. Angew Chem Int Ed Engl. 2020 Aug 17;59(34):14481-14489.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported