N-Acetylhexosamine kinase (NahK)

N-Acetylhexosamine kinase (NahK)

• CAS Number: 1609980-80-4
• UNSPSC Description: N-Acetylhexosamine kinase (NahK) is an anomeric kinase acting on a glucose-type substrate. N-Acetylhexosamine kinase catalyzes the phosphorylation of GlcNAc or GalNAc at the anomeric C1 position with ATP to form N-acetylhexosamine 1-phosphate (GlcNAc-1P/GalNAc-1P)[1][2].
• Target Antigen: Endogenous Metabolite
• Type: Enzyme
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/n-acetylhexosamine-kinase-nahk.html
• Solubility: 10 mM in DMSO
• Smiles: [N-Acetylhexosamine kinase (NahK)]
• References & Citations: [1]Sato M, et al. Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase. Biochim Biophys Acta. 2015 May;1854(5):333-40.|[2]Wang KC, et al. Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes. Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1401-10.
• Shipping Conditions: Blue Ice
• Storage Conditions: Store at -20°C for 2 years
• Clinical Information: No Development Reported