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(1S,2S,3R)-DT-061

CAT:
804-HY-112929B-05
Size:
100 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
(1S,2S,3R)-DT-061 - image 1

(1S,2S,3R)-DT-061

  • CAS Number: 1809427-20-0
  • UNSPSC Description: (1S,2S,3R)-DT-061 is an enantiomer of DT-061 (HY-112929). DT-061 is an orally active activator of protein phosphatase 2A (PP2A). (1S,2S,3R)-DT-061 can be used as a negative control in the research of KRAS-mutant and MYC-driven lung cancer tumorigenesis[1].
  • Target Antigen: Phosphatase
  • Type: Reference compound
  • Related Pathways: Metabolic Enzyme/Protease
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/1s-2s-3r-dt-061.html
  • Purity: 99.73
  • Solubility: DMSO : 125 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
  • Smiles: O=S(C1=CC=C(OC(F)(F)F)C=C1)(N[C@@H]2[C@@H](O)[C@H](N3C4=C(C=CC=C4)OC5=CC=CC=C35)CCC2)=O
  • Molecular Weight: 520.52
  • References & Citations: [1]Kauko O, et al. PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Sci Transl Med. 2018 Jul 18;10(450). pii: eaaq1093.
  • Shipping Conditions: Blue Ice
  • Storage Conditions: -20°C, 3 years (Powder)
  • Clinical Information: No Development Reported

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