HIF-2α-IN-4
CAT:
804-HY-136748-04
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HIF-2α-IN-4
- CAS Number: 882268-69-1
- UNSPSC Description: HIF-2α-IN-4 is a potent inhibitor of hypoxia inducible factor-2α (HIF-2α) translation, with an IC50 of 5 μM. HIF-2α-IN-4 decreases both constitutive and hypoxia-induced HIF-2α protein expression. HIF-2α-IN-4 links its 5'UTR iron-responsive element to oxygen sensing[1].
- Target Antigen: HIF/HIF Prolyl-Hydroxylase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hif-2α-in-4.html
- Smiles: O=C(C1=C(N/N=C(C#N)/S(=O)(C)=O)C=CS1)OC
- Molecular Weight: 287.32
- References & Citations: [1]Zimmer M, et al. Small-molecule inhibitors of HIF-2α translation link its 5'UTR iron-responsive element to oxygen sensing. Mol Cell. 2008;32(6):838-848.
- Shipping Conditions: Room Temperature