Suc-Ala-Glu-Pro-Phe-pNA

Suc-Ala-Glu-Pro-Phe-pNA

• CAS Number: 128802-76-6
• UNSPSC Description: Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc[1][2].
• Target Antigen: Biochemical Assay Reagents
• Type: Dye Reagents
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/suc-ala-glu-pro-phe-pna.html
• Purity: 98.52
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: O=C(N(CCC1)[C@@H]1C(N[C@H](C(NC(C=C2)=CC=C2[N+]([O-])=O)=O)CC3=CC=CC=C3)=O)[C@H](CCC(O)=O)NC([C@H](C)NC(CCC(O)=O)=O)=O
• Molecular Weight: 682.68
• References & Citations: [1]Subedi A, et al. Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening. Biochem Biophys Res Commun. 2016 Jun 3;474(3):528-533. |[2]Liu C, et al. Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1. Mol Med Rep. 2017 May;15(5):3210-3214.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported