TNFRSF1A, Rat (HEK293, His)
CAT:
804-HY-P74504-01
Size:
2 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TNFRSF1A, Rat (HEK293, His)
- UNSPSC Description: TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNFRSF1A Protein, Rat (HEK293, His) is expressed by HEK293 and has a transmembrane region (M1-A211) with a His tag at the C-terminus[1].
- Type: Recombinant Proteins
- Assay Protocol: https://www.medchemexpress.com/cytokines/tnfrsf1a-protein-rat-hek293-his.html
- Purity: 95.00
- Smiles: LVPSLGDREK RDNLCPQGKY AHPKNNSICC TKCHKGTYLV SDCPSPGQET VCEVCDKGTF TASQNHVRQC LSCKTCRKEM FQVEISPCKA DMDTVCGCKK NQFQRYLSET HFQCVDCSPC FNGTVTIPCK EKQNTVCNCH AGFFLSGNEC TPCSHCKKNQ ECMKLCLPPV ANVTNPQDSG TA
- Molecular Weight: Approximately 30-40 kDa due to glycosylation
- References & Citations: [1]Wajant H, et, al. Tumor necrosis factor signaling. Cell Death Differ. 2003 Jan;10(1):45-65.|[2]Fu Q, et, al. miR-29a up-regulation in AR42J cells contributes to apoptosis via targeting TNFRSF1A gene. World J Gastroenterol. 2016 May 28;22(20):4881-90.|[3]Zhou S, et, al. Bioinformatics Analysis Identifies TNFRSF1A as a Biomarker of Liver Injury in Sepsis TNFRSF1A is a Biomarker for Septic Liver Injury. Genet Res (Camb). 2022 Oct 15;2022:1493744.|[4]Egusquiaguirre SP, et, al. The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells. Neoplasia. 2018 May;20(5):489-498.
- Shipping Conditions: Blue Ice
- Storage Conditions: Stored at -20°C for 2 years