KI696
CAT:
804-HY-101140-04
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
KI696
- CAS Number: 1799974-70-1
- UNSPSC Description: KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction[1].
- Target Antigen: Keap1-Nrf2
- Type: Reference compound
- Related Pathways: NF-κB
- Applications: COVID-19-immunoregulation
- Field of Research: Metabolic Disease; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/KI696.html
- Purity: 99.26
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: COC1=C(N2C)C(N=N2)=CC([C@H](C3=CC(CN(C[C@H]4C)S(=O)(C5=CC=CC=C5O4)=O)=C(C)C=C3)CC(O)=O)=C1
- Molecular Weight: 550.63
- References & Citations: [1]Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28;59(8):3991-4006.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported