2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside

• CAS Number: 82373-94-2
• UNSPSC Description: 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions[1][2].
• Target Antigen: ERK; NF-κB
• Type: Natural Products
• Related Pathways: MAPK/ERK Pathway;NF-κB;Stem Cell/Wnt
• Field of Research: Neurological Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/2,3,5,4_acute_-Tetrahydroxystilbene-2-O-_beta_-D-glucoside.html
• Purity: 99.91
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
• Smiles: OC1=CC(O)=CC(/C=C/C2=CC=C(O)C=C2)=C1O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO
• Molecular Weight: 406.39
• References & Citations: [1]Kimura Y et al. Effects of stilbenes on arachidonate metabolism in leukocytes. Biochim Biophys Acta. 1985 Apr 25;834(2):275-8.|[2]Chen Z, et al. 2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevention of lipopolysaccharide-induced depressive-like behaviors in mice involves neuroinflammation and oxido-nitrosative stress inhibition. Behav Pharmacol. 2017 Aug;28(5):365-374. |[3]Sun L, et al. Investigation on the mechanism of 2,3,4',5-Tetrahydroxystilbene 2-o-D-glucoside in the treatment of inflammation based on network pharmacology. Comput Biol Med. 2022 Jun;145:105448.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported