Sucralose-d6

CAT:

804-HY-N0614S

Size:

1 mg

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CAS Number: 1459161-55-7
UNSPSC Description: Sucralose-d6 is deuterium labeled Sucralose. Sucralose (E955; Trichlorosucrose) is a non-nutritive artificial sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents[1][2].
Target Antigen: Endogenous Metabolite
Type: Isotope-Labeled Compounds
Related Pathways: Metabolic Enzyme/Protease
Applications: Cancer-programmed cell death
Field of Research: Cancer
Solubility: 10 mM in DMSO
Smiles: Cl[C@@H]1[C@@H]([C@H]([C@H](O[C@@H]1C([2H])(O)[2H])O[C@]2([C@H]([C@@H]([C@H](O2)C([2H])(Cl)[2H])O)O)C([2H])(Cl)[2H])O)O
Molecular Weight: 403.67
References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]M S, et al. Sucralose administered in feed, beginning prenatally through lifespan, induces hematopoietic neoplasias in male swiss mice. Int J Occup Environ Health. 2016 Jan;22(1):7-17.|[3]Nabanita Kundu, et al. Sucralose promotes accumulation of reactive oxygen species (ROS) and adipogenesis in mesenchymal stromal cells. Stem Cell Res Ther. 2020 Jun 26;11(1):250.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported