Cathepsin inhibitor 1

Cathepsin inhibitor 1

• CAS Number: 225120-65-0
• UNSPSC Description: Cathepsin inhibitor 1 (Compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively. Cathepsin inhibitor 1 is promising for research of osteoarthritis[1].
• Target Antigen: Cathepsin
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-Kinase/protease
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/cathepsin-inhibitor-1.html
• Purity: 98.89
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C1=CC(C(C)(C)C)=NN1C)N[C@@H](CC2=CC=CC(Cl)=C2)C(NCC#N)=O
• Molecular Weight: 401.89
• References & Citations: [1]Asaad N, et, al. Dipeptidyl nitrile inhibitors of Cathepsin L. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4280-3.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported