DB-3-291
CAT:
804-HY-137345-03
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DB-3-291
- CAS Number: 2769753-64-0
- UNSPSC Description: DB-3-291 is potent and selective PROTAC CSK degrader, with a Kd of 1 nM (Pink: CSK ligand (HY-131669); Blue: E3 ligase ligand (HY-103597); Black: linker (HY-N2407))[1].
- Target Antigen: PROTACs; Toll-like Receptor (TLR)
- Type: Reference compound
- Related Pathways: Immunology/Inflammation;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/db-3-291.html
- Smiles: O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=CC=C3OCC(NCCCCNC(CN4CCN(C5=CC(NC6=NC=C(C(NC7=C(Cl)C=CC=C7C)=O)S6)=NC(C)=N5)CC4)=O)=O)=O
- Molecular Weight: 886.37
- References & Citations: [1]Donovan KA, et, al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020 Dec 10;183(6):1714-1731.e10.
- Shipping Conditions: Blue Ice