PROTAC STAT3 degrader-3
CAT:
804-HY-163502
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PROTAC STAT3 degrader-3
- UNSPSC Description: PROTAC STAT3 degrader-3 (S3D1) is a STAT3 PROTAC degrader with anticancer activity (Structural notes: (Blue: Cereblon ligand (HY-10984), Black: linker; Pink: Pentafluorobenzenesulfonamide(Me)-CH2-CONH-benzamide (HY-163526))[1].
- Target Antigen: PROTACs; STAT
- Type: Reference compound
- Related Pathways: JAK/STAT Signaling;PROTAC;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-stat3-degrader-3.html
- Solubility: 10 mM in DMSO
- Smiles: CN(S(=O)(C1=C(C(F)=C(C(F)=C1F)F)F)=O)CC(NC2=CC=C(C=C2)C(NCCOCCNC3=C4C(N(C(C4=CC=C3)=O)C5CCC(NC5=O)=O)=O)=O)=O
- Molecular Weight: 780.68
- References & Citations: [1]Wang Kefeng, et al. STAT3 inhibitor, PROTAC molecule, and preparation methods and applications thereof. U.S, CN117720443, 2024-03-19.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported