Phytosphingosine

Phytosphingosine

• Background: Phytosphingosine is a naturally occurring component found in yeast, plants and animals. In yeast, it is involved in mediating the heat stress response. Phytosphingosine has been found to be pro-apoptotic in certain cancer cell lines. It is thought to activate the p38 MAPK pathway, followed by release of cytochrome c and activation of caspase 3, ultimately leading to programed cell death.
• Description: Kinase Activator
• Product Name Alternative: (2S,3R,4R)-Octadecane-1,2,3,4-tetraol
• CAS Number: 554-62-1
• UNSPSC: 41116105
• Source: Isolated from Saccharomyces cerevisiae
• Purity: >98% (TLC); NMR (Conforms)
• Weight: 0.005
• Format: White powder
• Solubility: Soluble to 2 mg/ml in ethanol
• Molecular Formula: C18H39NO3
• Molecular Weight: 317.5
• Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• References & Citations: 1. Fischer C., et al. (2013) Skin Pharmacol Physiol. 26(1): 36-44.