Acrolein Antibody: PerCP
CAT:
400-SMC-505D-PCP
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Acrolein Antibody: PerCP
- Background: Lipid peroxidation occurs when oxidizing agents attack carbon-carbon double bonds found in unsaturated lipids. In addition to membrane degradation, oxidation end-products have been found to damage cell viability through their mutagenic and toxic properties. These downstream functional consequences facilitate the development of disease and premature aging. Acrolein is an electrophilic conjugated aldehyde that is a terminal product of lipid peroxidation. Acrolein is highly mutagenic and reacts with nucleophilic functional groups in DNA and proteins such as cysteine, histidine, and lysine residues (1).
- Description: Mouse Anti-Acrolein conjugated protein Monoclonal IgG1
- Specifications: Specific for Acrolein modified proteins. Does not detect free acrolein. Does not cross-react with Crotonaldehyde, Hexanoyl Lysine, 4-Hydroxy-2-hexenal, 4-Hydroxy nonenal, Malondialdehyde, or Methylglyoxal modified proteins.
- Product Name Alternative: Acrolein modified protein Antibody, Acrolein conjugated protein Antibody, 2-Propen-1-one Antibody, 2-propenal Antibody, Acraldehyde Antibody, Acrolein Antibody, Acrylic aldehyde Antibody, Protein-bound Acrolein Antibody
- Synonyms: Acrolein Antibody, Clone 10A10: PerCP
- CAS Number: 9007-83-4
- UNSPSC: 12352203
- Host: Mouse
- Species Reactivity: Species Independent
- Immunogen: Synthetic Acrolein modified Keyhole Limpet Hemocyanin (KLH).
- Target: Acrolein
- Clonality: Monoclonal
- Isotype: IgG1
- Clone: 10A10
- Conjugation: PerCP
- Validated Applications: WB, IHC, ICC/IF, ELISA
- Purification: Protein G Purified
- Limit Of Detection: A 1:1000 dilution of SMC-505 was sufficient for detection of Acrolein in 2 µg of Acrolein conjugated to BSA by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary Antibody.
- Concentration: 1 mg/ml
- Dilution: WB (1:1000); ICC/IF (1:50); FACS (1:50); FCM (1:50); ELISA (1:1000); IHC (1:100); optimal dilutions for assays should be determined by the user.
- Weight: 0.1
- Buffer: 95.64mM Phosphate, 2.48mM MES and 2mM EDTA
- Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- References & Citations: 1. Takabe, W. et al. (2001) Carcinogenesis. 22 (6): 935-957