HOKU-81
CAT:
804-HY-50291-02
Size:
10 mM / 1 mL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HOKU-81
- CAS Number: 58020-43-2
- UNSPSC Description: HOKU-81 (4-Hydroxytulobuterol) is one of the metabolites of Tulobuterol (HY-B1810). HOKU-81 is a potent and selective β2-adrenoceptor stimulant. HOKU-81 has bronchodilating effect[1][2].
- Target Antigen: Adrenergic Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: COVID-19-immunoregulation
- Field of Research: Cardiovascular Disease; Endocrinology
- Assay Protocol: https://www.medchemexpress.com/HOKU-81.html
- Purity: 95.0
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: ClC1=C(C(O)CNC(C)(C)C)C=CC(O)=C1
- Molecular Weight: 243.734
- References & Citations: [1]Kubo S, Matsubara I, Yamazaki M et al. Pharmacological studies of 1-(2-chloro-4-hydroxyphenyl)-2-t-butylaminoethanol (HOKU-81), a new bronchodilator. 1st Communication: Bronchodilator and cardiovascular actions. Arzneimittelforschung. 1980;30(8):1272-8.|[2]Gomi Y, Shirahase H, Funato H. Effects of 1-(2-chloro-4-hydroxyphenyl)-t-butylaminoethanol (HOKU-81), a new bronchodilator, on isolated trachea and atria of guinea pig. Jpn J Pharmacol. 1979 Aug;29(4):515-24.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported