Miglustat

CAT:

804-HY-17020-03

Size:

10 mg

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CAS Number: 72599-27-0
UNSPSC Description: Miglustat (N-Butyldeoxynojirimycin) is an orally active and reversible ceramide glucosyltransferase inhibitor. Miglustat can be used for the research of type I gaucher disease[1].
Target Antigen: Glucosylceramide Synthase (GCS)
Type: Reference compound
Related Pathways: Neuronal Signaling
Applications: Neuroscience-Neuromodulation
Field of Research: Inflammation/Immunology; Neurological Disease
Assay Protocol: https://www.medchemexpress.com/miglustat.html
Solubility: H2O : 250 mg/mL (ultrasonic)
Smiles: O[C@H]1[C@H](O)[C@@H](CO)N(CCCC)C[C@@H]1O
Molecular Weight: 219.28
References & Citations: [1]Maria Cristina Dechecchi, et al. Anti-inflammatory effect of miglustat in bronchial epithelial cells. J Cyst Fibros. 2008 Nov;7(6):555-65. |[2]G D'Arcangelo, et al. Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease. Neural Plast. 2016:2016:3830424. Cell Rep. 2022 Jul 5;40(1):111049.|Nat Commun. 2024 Aug 14;15(1):6970.|Preprints. 2023 Dec 20.|Cell. 2019 Dec 12;179(7):1483-1498.e22.
Shipping Conditions: Room Temperature
Clinical Information: Launched