ULK1 rabbit pAb

• Description: Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells. similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. similarity: Contains 1 protein kinase domain. subunit: Interacts with GABARAP and GABARAPL2. tissue specificity: Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.
• Synonyms: ULK1; KIAA0722; Serine/threonine-protein kinase ULK1; Autophagy-related protein 1 homolog; ATG1; hATG1; Unc-51-like kinase 1
• Gene ID: 8408
• UniProt: O75385
• Cellular Locus: Cytoplasm, cytosol. Preautophagosomal structure. Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome..
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthesized peptide derived from the C-terminal region of human ULK1.
• Clonality: Polyclonal
• Validated Applications: IHC, IF, WB, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:500-2000,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.