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CPN cat rabbit pAb

CAT:
855-ES2041-02
Size:
100 μL
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
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CPN cat rabbit pAb

  • Description: Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008],
  • Synonyms: CPN1; ACBP; Carboxypeptidase N catalytic chain; CPN; Anaphylatoxin inactivator; Arginine carboxypeptidase; Carboxypeptidase N polypeptide 1; Carboxypeptidase N small subunit; Kininase-1; Lysine carboxypeptidase; Plasma carboxypeptidase B; S
  • Gene ID: 1369
  • UniProt: P15169
  • Cellular Locus: Secreted, extracellular space.
  • Host: Rabbit
  • Species Reactivity: Human, Rat, Mouse,
  • Immunogen: The antiserum was produced against synthesized peptide derived from human CPN1. AA range:409-458
  • Clonality: Polyclonal
  • Validated Applications: WB, ELISA
  • Stability: 1 year
  • Concentration: 1 mg/mL
  • Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
  • Molecular Weight: total 52kD,Cleaved 48kD
  • Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Datasheet