NM23A Rabbit rabbit pAb

• Description:

  This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008],

• Synonyms:

  NME1

• Gene ID:

  4830

• UniProt:

  P15531

• Cellular Locus:

  Cytoplasm. Nucleus. Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Recombinant Protein of NM23A of NME1

• Clonality:

  Polyclonal

• Validated Applications:

  IHC, IF

• Stability:

  1 year

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:100-200

• Molecular Weight:

  17kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.