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A Cyclase V/VI rabbit pAb

CAT:
855-ES1555-02
Size:
100 μL
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
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A Cyclase V/VI rabbit pAb

  • Description: This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
  • Synonyms: ADCY5; Adenylate cyclase type 5; ATP pyrophosphate-lyase 5; Adenylate cyclase type V; Adenylyl cyclase 5; ADCY6; KIAA0422; Adenylate cyclase type 6; ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca(2+)-inhibitabl
  • Gene ID: 111/112
  • UniProt: O95622/O43306
  • Cellular Locus: Cell membrane ; Multi-pass membrane protein. Cell projection, cilium.
  • Host: Rabbit
  • Species Reactivity: Human, Mouse, Rat
  • Immunogen: The antiserum was produced against synthesized peptide derived from human ADCY5/6. AA range:931-980
  • Clonality: Polyclonal
  • Validated Applications: WB, IHC, IF, ELISA
  • Stability: 1 year
  • Concentration: 1 mg/mL
  • Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
  • Molecular Weight: 138kD
  • Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Datasheet