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Vapendavir (diphosphate)

CAT:
804-HY-106254A-04
Size:
25 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Vapendavir (diphosphate) - image 1

Vapendavir (diphosphate)

  • CAS Number: 1198151-75-5
  • UNSPSC Description: Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].
  • Target Antigen: Enterovirus
  • Type: Reference compound
  • Related Pathways: Anti-infection
  • Applications: COVID-19-anti-virus
  • Field of Research: Infection; Inflammation/Immunology
  • Assay Protocol: https://www.medchemexpress.com/vapendavir-diphosphate.html
  • Purity: 98.75
  • Solubility: DMSO : 6.75 mg/mL (ultrasonic)
  • Smiles: CCOC1=NOC2=CC(OCCC3CCN(C4=CC=C(C)N=N4)CC3)=CC=C12.OP(O)(O)=O.OP(O)(O)=O
  • Molecular Weight: 578.45
  • References & Citations: [1]Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2.|[2]Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.Norwegian University of Science and Technology. 2023 May.|ACS Infect Dis. 2020 May 8;6(5):882-890.|SSRN. 2024 Apr 19.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
  • Clinical Information: Phase 2